PSC Literature Logo
  Primary Sclerosing Cholangitis Literature  
 
Home Page
 
FAQ
 
PSC Partners
 
www Resources
 
Scientific Literature
 
Genes
 
Pathways
 
Miscellaneous
 
PubMed Search
 
PubChem Search
 
Scirus Search
 
Site Statistics
 

Metabolic Pathways

Pathway Projector (zoomable user interface for systems biology)

Metabolic Pathway Links in "ExPASy":

the digitized version of the Roche Applied Science "Biochemical Pathways" wall chart

[view entire chart as thumbnails]

  • Cholesterol Metabolism (Images G10 & H10)
      Cholesterol ----> 7a-Hydroxycholesterol
      7a-Hydroxycholesterol <---> 7a,12a-Dihydroxycholest-4-en-3-one
      Cholesterol ---> D4-Cholesten-3-on
      Cholesterol ---> Coprostanol
      Cholesterol ---> Cholesterol Ester
      Cholesterol ---> 22B-Hydroxycholesterol ---> 20a,22B-Dihydroxycholesterol
      22B-Hydroxycholesterol ---> 20a,22B-Dihydroxycholesterol
  • Cholesterol Metabolism (Images H10 & I10)
      7a-Hydroxycholesterol <---> 7a,12a-Dihydroxycholest-4-en-3-one
      7a,12a-Dihydroxycholest-4-en-3-one ---> 7a,12a-Dihydroxy-5B-cholestan-3-one
      7a,12a-Dihydroxycholest-4-en-3-one ---> 7a-Hydroxy-5B-cholestan-3-one
      22B-Hydroxycholesterol ---> 20a,22B-Dihydroxycholesterol
      22B-Hydroxycholesterol ---> 17a,20a-Dihydroxycholesterol
  • Bile Acid Synthesis (Images I10 & J10)
      7a,12a-Dihydroxy-5B-cholestan-3-one <---> 3a,7a,12a-Trihydroxy-5B-cholestane
      3a,7a,12a-Trihydroxy-5B-cholestane ----> 3a,7a,12a,26-Tetrahydroxy-5B-cholestane
      7a-Hydroxy-5B-cholestan-3-one ---> 3a,7a-Dihydroxy-5B-cholestane
      3a,7a-Dihydroxy-5B-cholestane ---> Chenodeoxycholate
  • Bile Acid Synthesis (Images J10 & K10)
      3a,7a,12a,26-Tetrahydroxy-5B-cholestane <---> 3a,7a,12a,-Trihydroxy-5B-cholestaoate
      3a,7a,12a-Trihydroxy-5B-cholestanoate ---> ---> Choloyl-CoA
      3a,7a,12a,26-Tetrahydroxy-5B-cholestanoate ---> 5B-Cyprinolsulfate
      5B-Cyprinolsulfate ---> Scymnol Sulfate
  • Bile Acid Synthesis (Images K10 & L10)
      Choloyl-CoA <---> Cholate
      Choloyl-CoA ---> Taurocholate
      Choloyl-CoA ---> Glycocholate
      Taurocholate <---> Cholate
      Glycocholate <---> Cholate
      Cholate ---> ---> Deoxycholate

Google
www psc-literature.org

PSC Partners Seeking a Cure (www.pscpartners.org)
Don and Ricky Safer
Ricky Safer e-mail: contactus@pscpartners.org


Last Update: 09/27/10